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Assistant Professor
Cincinnati Children's Hospital,
Division of Human Genetics

 
ImmunologistMolecular Biologist, CRISPR& RNAseq expertNovice Bioinformatician

Yuriy Baglaenko, PhD

I'm a postdoctoral fellow working in the Boston area with a keen interest in understanding the genetics of autoimmunity. I enjoy creating and expanding upon cutting edge technologies to answer biological questions in Type 1 Diabetes and Rheumatoid Arthritis. In my spare time, I write music (it's not terrible)

 Immunologist  Tinkerer Musician  

 Molecular Biologist    Writer  Geneticist

I research I engage I lead 

I am a scientist. I believe in openness, collaboration, and scientific integrity. 

During my Ph.D. studies, I (with my close friend Charles) founded IMMpress Magazine,  a student-led initiative in the Department of Immunology to promotes these principles. Check it out, it's still going strong. 

For my various efforts,  I've been recognized with some awards. I am particularly proud of: the CIHR doctoral fellowship, the Hardi Cinader prize for excellence in science and arts,  and the Immunology Science Outreach award. 

 

I am also decidedly proud of bring involved with Let's Talk Science, a nationwide (Canadian) charitable organization focused on education and outreach in science, technology, engineering and mathematics for elementary and high school students.   

In my research, I have had the pleasure of being apart of exceptional and supportive scientific groups that have fostered inter-lab and inter-disciplinary collaborations. Many of my publications, published and under-preparation, arose from these collaborative efforts with cellular immunologists, biochemists, rheumatologists, neurologists, and bioinformaticians.

 

See some highlights below. 

Figure1_v11.jpg
RNAseq & CRISPR in T cells

Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci

Fig 2.jpg
CRISPRing B cells

Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins

Fig 3_v8.jpg
Pre-clinical Autoimmunity

The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease

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